Sexually transmitted infections (STIs) in female. Prior preterm labor in the current pregnancy. Women with PPROM in previous pregnancy are at increased risk for recurrence in next pregnancy. Subclinical intrauterine infection is a major predisposing factor, especially at early gestation. PPROM occurs in 3% of all pregnancies and is responsible for approximately 30% of all preterm deliveries. PROM occurs in approximately 10% of all pregnancies, and in 70% of these cases, it occurs in pregnancies at term. Rupture of membranes for >24 h before delivery is called prolonged rupture of membranes. When the rupture of membranes occurs before 37 completed weeks but before the onset of labor, it is called preterm prelabor rupture of membranes. When the rupture of membranes occurs beyond 37 weeks but before the onset of labor, it is called term prelabor rupture of membranes.ĥ.2.3 Preterm Prelabor Rupture of Membranes (PPROM) Prelabor rupture of membranes is defined as rupture of membranes before the onset of labor.ĥ.2.2 Term Prelabor Rupture of Membranes (TPROM) While intra-amniotic infection and its sequelae are the primary maternal risks, prematurity is the principal risk to the fetus which can lead to increased neonatal morbidity and mortality.ĥ.2.1 Prelabor Rupture of Membranes (PROM) Several issues need to be considered in formulating a plan of management. PPROM is far more difficult to manage than PROM at term. Preterm prelabor rupture of membranes (PPROM) is rupture of membranes prior to 37 weeks of gestation, but before the onset of labor. Prelabor rupture of membranes (PROM) remains a subject of great clinical relevance and a problem encountered by each and every obstetrician in day-to-day practice.
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